Thursday, January 13, 2011

Gastroparesis

http://www.mamashealth.com/stomach/gastroparesis.asp


What is Gastroparesis?
Gastroparesis is delayed stomach emptying. Gastroparesis often occurs in people with type 1 diabetes or type 2 diabetes.
Symptoms of Gastroparesis?
The most common symptoms of gastroparesis are:
  • nausea
  • vomiting of undigested food
  • full stomach when you eat a small amount of food
  • weight loss with normal eating
  • abdominal bloating
  • heart burn
What Causes Gastroparesis?
Gastroparesis is caused by impairment of the vagus nerve. The vagus nerve is responsible for mediating many automatic functions of the body, including heart rate and digestion. If the vagus nerve is not working properly, the muscles of the stomach and intestines do not work normally, and the movement of food is slowed or stopped.

What happens during Gastroparesis?
When a person has gastroparesis, the stomach is able to receive food from the esophagus but it is unable to release the food to the small intestine. When this happens, the stomach acid can travel up the esophagus causing a burning sensation in the middle of the chest (heartburn).
As a result of having gastroparesis, the stomach may feel full after small meals. This occurs because the stomach may not have emptied its contents from previous meal(s). In extreme cases, several meals will accumulate in the stomach and cause severe bloating.
How does Gastroparesis affect Diabetics?
Gastroparesis can make it difficult for people with diabetes to control their blood sugar levels. This occurs because if the stomach empties too slowly, it can have the same effects on blood sugar as skipping a meal. Blood sugars will plummet and rise depending on when the stomach empties.
How is Gastroparesis Diagnosed?
Your doctor can diagnose gastroparesis by performing the following tests:
  • R-R interval study
  • Gamma-Ray Technetium scan
  • Barium Hamburger test

Treatment Options for Gastroparesis?
Gastroparesis can be treated. The most common treatments for gastroparesis are:
  • medications
  • special exercises during and after meals
  • special massages duing and after meals
  • modification of meal plan


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http://en.wikipedia.org/wiki/Gastroparesis



Gastroparesis

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Gastroparesis
Classification and external resources
ICD-10 K31.8
ICD-9 536.3
DiseasesDB 32575
MedlinePlus 000297
MeSH D018589
Gastroparesis, also called delayed gastric emptying, is a medical condition consisting of a paresis (partial paralysis) of the stomach, resulting in food remaining in the stomach for a longer period of time than normal. Normally, the stomach contracts to move food down into the small intestine for digestion. The vagus nerve controls these contractions. Gastroparesis may occur when the vagus nerve is damaged and the muscles of the stomach and intestines do not work normally. Food then moves slowly or stops moving through the digestive tract.

Contents

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[edit] Causes

Gastroparesis may be chronic or transient; transient gastroparesis may arise in acute illness of any kind, with the use of certain cancer treatments or other drugs which affect digestive action, or due to anorexia nervosa, bulimia and other abnormal eating patterns.
Chronic gastroparesis is frequently due to autonomic neuropathy. This may occur in people with type 1 diabetes or type 2 diabetes. The vagus nerve becomes damaged by years of high blood glucose, resulting in gastroparesis. Gastroparesis has also been associated with various autoimmune diseases and syndromes, such as fibromyalgia and Parkinson's disease, and may occur as part of a mitochondrial disorder.
Chronic gastroparesis can also be caused by other types of damage to the vagus nerve, such as abdominal surgery.[1]
Idiopathic gastroparesis (gastroparesis with no known cause) accounts for a third of all chronic cases; it is thought that many of these cases are due to an autoimmune response triggered by an acute viral infection. "Stomach flu", mononucleosis, and others have been anecdotally linked to the onset of the condition, but no systematic study has proven a link.
Gastroparesis sufferers are disproportionately female. One possible explanation for this finding is that women have an inherently slower stomach emptying time than men.[2] A hormonal link has also been suggested, as gastroparesis symptoms tend to worsen the week before menstruation, when progesterone levels are highest.[3] Neither theory has been proven definitively.

[edit] Signs and Symptoms

The most common symptoms of gastroparesis are[4]
  • Chronic nausea
  • Vomiting (especially of undigested food)
  • Early satiety
Other symptoms include
  • Heartburn
  • Weight loss
  • Weight gain (often attributed to the 'starvation mode' effect)
  • Abdominal pain
  • Abdominal bloating
  • Erratic blood glucose levels
  • Lack of appetite
  • Gastroesophageal reflux
  • Spasms of the stomach wall
Morning nausea may also indicate gastroparesis. It is important to note that vomiting may not occur in all cases, as sufferers may learn to adjust their diets to include only small amounts of food.[5]

[edit] Diagnosis and Treatment

Gastroparesis can be diagnosed with tests such as x rays, manometry, and gastric emptying scans. The clinical definition for gastroparesis is based solely on the emptying time of the stomach and not on other symptoms, and severity of symptoms does not necessarily correlate with the severity of gastroparesis. Therefore, some patients may have marked gastroparesis with few, if any, serious complications.
Treatment includes dietary changes (low-fiber and low-residue diets, and in some cases, restrictions on fat and/or solids), oral medications such as metoclopramide (Reglan, Maxolon, Clopra), cisapride (Propulsid)(no longer available in the US), erythromycin (E-Mycin, Erythrocin, Ery-Tab, EES) and domperidone (Motilium); adjustments in insulin dosage for those with diabetes, a jejunostomy tube, parenteral nutrition, implanted gastric neurostimulators ("stomach pacemakers"), or botulinum toxin.
Viagra, which increases blood flow to the genital area, is also being used by some practitioners to stimulate the GI tract in diabetic gastroparesis.
The antidepressant mirtazapine has also proven effective in the treatment of gastroparesis unresponsive to conventional treatment. This is due to its anti-emetic and appetite stimulant properties. Mirtazapine acts on the same serotonin receptor (5-HT3) as the popular anti-emetic ondansetron.[6]

[edit] Complications

Primary complications of gastroparesis include:
  • Fluctuations in blood glucose due to unpredictable digestion times (in diabetic patients)
  • General malnutrition due to the symptoms of the disease (which frequently include vomiting and reduced appetite) as well as the dietary changes necessary to manage it
  • Severe fatigue and weight loss due to calorie deficit
  • Intestinal obstruction due to the formation of bezoars (solid masses of undigested food)
  • Bacterial infection due to overgrowth in undigested food
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http://www.drweil.com/drw/u/QAA400595/Natural-Treatment-for-Gastroparesis.html

The most common cause of gastroparesis is diabetes. Here, high blood sugar affects the health of nerves throughout the body and can damage the vagus nerve. Other causes include surgery on the stomach, viral infections, eating disorders (anorexia nervosa or bulimia), medications that slow contractions in the intestine, and gastroesophageal reflux disease (GERD).

Sometimes no cause can be found - these cases are referred to as idiopathic gastroparesis.


I discussed your question with Gerard Mullin, M.D., associate professor of medicine and an integrative gastroenterologist at Johns Hopkins Hospital. He told me that acupuncture and electroacupuncture have been shown in randomized trials to be effective for gastroparesis, and that a study published in the European Journal of Gastroenterology & Hepatology in May, 2008, found that ginger accelerates gastric emptying. The dose used in the study was three capsules containing a total of 1,200 mg of ginger. Another natural remedy that may prove useful is Swedish bitters - an herbal concoction. The typical dose is one tablespoon before meals. Dr. Mullin also recommended visceral manipulation-massage, a type of massage that aims to release stress and tension from abdominal organs.



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http://www.ucsfhealth.org/conditions/gastroparesis/treatment.html


Dietary Requirements

Therapy for gastroparesis requires that you follow certain dietary requirements, such as eating small meals throughout the day and avoiding foods that are difficult to digest. These include fatty foods, legumes, lentils and citrus fruits. If you have gastroparesis as a complication of diabetes, you may need to increase your insulin therapy.



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Гастропарез

 Гастропаре́з — расстройство пищеварения, характеризующееся снижением активности мышечного аппарата желудка


Симптомы

Первичные симптомы гастропареза - тошнота и рвота. Другие проявления гастропареза: боль в животе, вздутие, раннее насыщение и, в серьезных случаях, потеря веса из-за снижения потребления пищи (из-за симптомов). Уменьшенное потребление пищи и ограничение видов пищи могут привести к пищевым дефицитам.
Рвота при гастропарезе обычно происходит после приемов пищи; однако, при серьезном гастропарезе, рвота может произойти не после приема пищи, а из-за накопления еды в желудке. Характерная рвота случается спустя несколько часов после еды, когда желудок максимально надувается из-за съеденной пищи и пищи, которая уже была в нем до последнего приема еды.
Иногда при гастропарезе развивается гастроэзофагеальная рефлюксная болезнь.


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